Pregnancy Heartburn
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Los Angeles Times Profiles Antiabortion Pastor Who Travels Southern Calif. In Mobile Pregnancy Clinic
The Los Angeles Times on Monday profiled Dave Wilkinson, an evangelical pastor who runs three Ventura County, Calif., pregnancy clinics that try to urge women not to have abortions...
Research Identifies New Mechanism Regulating Embryonic Development
A Princeton University-led research team has discovered that protein competition over an important enzyme provides a mechanism to integrate different signals that direct early embryonic development. The work suggests that these signals are combined long before they interact with the organism's DNA, as was previously believed, and also may inform new therapeutic strategies to fight cancer...
Low-Income Women Living In Small Cities Have Higher Chance Of Obesity
A recent Kansas State University study found that the availability of supermarkets -- rather than the lack of them -- increased the risk of obesity for low-income women living in small cities. This suggests that policies to increase healthful eating behaviors might need to be tailored based on geographic location...
Scientists' Understanding Of Limb Growth Altered By Roving 'Sonic Hedgehog' Gene
Sonic hedgehog, a gene that plays a crucial rule in the positioning and growth of limbs, fingers and toes, has been confirmed in an unexpected place in the embryos of developing mice - the layer of cells that creates the skin. Named for a video game character, Sonic hedgehog describes both a gene and the protein it produces in the body...
Utah Gov. Signs Revised Bill Allowing Criminal Charges Against Women For Illegal Abortions
Utah Gov. Gary Herbert (R) on Monday signed a bill (HB 462) that would allow prosecutors to bring criminal homicide charges against women who arrange illegal abortions, the Salt Lake Tribune reports (Gehrke, Salt Lake Tribune, 3/8). An earlier version of the bill (HB 12), sponsored by state Rep...
New York Times Examines Factors Affecting VBAC Rates As NIH Conference Begins
The New York Times on Tuesday examined efforts to increase rates of vaginal births after caesarean sections at the Tuba City Regional Health Care Corporation, a small hospital run by the Navajo Nation and financed partially by the Indian Health Services...
Malaria In Pregnant Women : A First Step Towards A New Vaccine
By managing to express the protein that enables red blood cells infected with the malaria agent Plasmodium falciparum to bind to the placenta and by deciphering its molecular mechanisms, a team of researchers from CNRS and the Institut Pasteur has taken an important first step in the development of a vaccine against pregnancy-associated malaria. Their work was published in the journal PNAS...
Elevated Levels Of Cobalt And Chromium Found In Offspring Of Moms With Metal-on-Metal Hip Implants
Women with metal-on-metal hip implants, where both the ball of the joint and the surface of the socket are made of metal, pass metal ions to their offspring during pregnancy, according to a study by researchers at Rush University Medical Center. The ions are the result of wear and corrosion as the metal parts rub against one another...
Study Finds Elevated Levels Of Cobalt And Chromium In Offspring Of Patients With Metal-On-Metal Hip Implants
Hip replacement patients with metal-on-metal (MoM) implants (both the socket and hip ball are metal) pass metal ions to their infants during pregnancy, according to a new study presented at the 2010 Annual Meeting of the American Academy of Orthopaedic Surgeons (AAOS)...
Researchers Find Exposure To BPA May Cause Permanent Fertility Defects
Researchers at Yale School of Medicine have discovered that exposure during pregnancy to Bisphenol A (BPA), a common component of plastics, causes permanent abnormalities in the uterus of offspring, including alteration in their DNA. The findings were reported in the March issue of Journal of the Federation of American Societies for Experimental Biology (FASEB J.). Led by Hugh S. Taylor, M.D...
Is Prenatal Screening For Rare Diseases Like Spinal Muscular Atrophy Too Costly?
Spinal Muscular Atrophy (SMA) is one of many serious disorders for which prenatal testing is available. SMA affects approximately 1 in 10,000 live births and is the leading genetic cause of infant mortality and the second most common autosomal recessive disorder, after cystic fibrosis...
Women's Group Support Can Improve Birth Outcomes
Community support groups can reduce neonatal mortality, and lower rates of maternal depression-provided that the population coverage is wide enough and the programmes are appropriately designed. These are the conclusions of two Articles, published Online First in The Lancet. Participatory women's groups have shown promise in trials in Nepal, reducing neonatal mortality by about one-third...
Pregnant Women Falling Short On Nutrition
Pregnant women are skimping on fruit and vegetables and gaining too much weight, according to a new Australian study. The research, in the journal Nutrition & Dietetics published by Wiley-Blackwell, found that expectant mothers are eating less than half the recommended servings of fruit and vegetables. And at least one in three put on more than the recommended weight gain for pregnancy...
Women's Support Groups Make Dramatic Improvements On Neonatal Survival Rates
Women's community groups have had a dramatic effect on reducing neonatal mortality rates in some of the poorest areas on India, according to a study published in the journal the Lancet. The groups provide a cost-effective intervention with added benefits such as reducing significantly maternal depression and improving decision-making amongst the women...
Successful Treatment Of Periodontal Disease Lowered Preterm Birth Incidences
Previous studies have explored the effect of periodontal treatment, irrespective of efficacy of treatment, in reducing infant prematurity. In a study titled "Risk of Preterm Birth Is Reduced with Successful Periodontal Treatment," lead researcher M. Jeffcott, and colleagues S. Parry and M. Sammel (all from the University of Pennsylvania, Philadelphia) and G. Macones (Washington University, St...
Utah Lawmaker Withdraws Bill To Charge Women Who Seek Illegal Abortions; Plans Revised Measure
Utah Rep. Carl Wimmer (R) on Thursday withdrew for revisions a bill (HB 12) that would have allowed sentences of up to life in prison for any woman whose fetus dies because of her intentional or reckless actions, the New York Times reports (Johnson, New York Times, 3/4). The legislation -- which had been sent to Gov...
Minn. Legislature Considers 'Abstinence-Plus' Sex Education Bill
A bill (SF 2645) in the Minnesota Legislature would require each school district to create an "abstinence-first" sex education curriculum with "age-appropriate" lessons on human sexuality and information about condoms and other contraceptives, the St. Paul Pioneer Press reports...
March Of Dimes President Dr. Jennifer L. Howse Wins Prestigious Humanitarian Award
The nation's champion for babies has received the 2010 Jimmy and Rosalynn Carter Humanitarian Award. Dr. Jennifer L. Howse, who has served as president of the March of Dimes since 1990, was honored March 2 by the National Foundation for Infectious Diseases (NIFD) at a ceremony at the Ritz Carlton in Tysons Corner, Va. "Dr...
Out-of-Hospital Births Increase After 15-Year Decline, Government Report States
Reversing a 15-year trend, the percentage of infants born at home rose slightly in 2005 and remained stable in 2006, according to a report published Wednesday in the Centers for Disease Control and Prevention's National Vital Statistics Reports, USA Today reports. Marian MacDorman, a demographer at CDC's National Center for Health Statistics, said it is not clear what caused the slight increase...
Women Community Support Groups Can Reduce Neonatal Mortality
Two articles published Online First in The Lancet report that community support groups can reduce neonatal mortality. In addition, they can lower rates of maternal depression, provided that the population coverage is wide enough and the programs are suitably designed. In trials in Nepal, participatory women's groups have shown promise. Neonatal mortality was reduced by about one-third...
Colo., 'Personhood' Measure Fails To Qualify For Ballot; Colo., Wyo., Finalize Bills On Violence Against Pregnant Women
The following summarizes recent action in Colorado and Wyoming related to a "personhood" initiative and bills addressing crimes against pregnant women...
News From The March Issue Of Chest
PREGNANT SMOKERS WITH ASTHMA HAVE INCREASED HEALTH RISKS Pregnant women with asthma who smoke have an increased risk for asthma symptoms and fetal growth abnormalities. Researchers from the Medical University of South Carolina observed 2,210 pregnant women with asthma to determine the effect of active and passive household smoking on asthma severity and obstetric/neonatal outcomes...
Drop In Calif. Teen Births Shows Effectiveness Of State's 'Enlightened Approach' To Pregnancy Prevention, Editorial Says
California governors of the past two decades "deserve praise for funding a wide array of programs aimed at combating teen births," a Sacramento Bee editorial states. The editorial notes that California is "bucking a national trend" of rising teen births. The number of births to California teens ages 15 through 19 dropped to 35.2 per 1,000 teens in 2008, down from 37...
Blogs Comment On Antiabortion Billboard Campaign, Health Reform Summit, Other Topics
The following summarizes selected women's health-related blog entries...
Women 40 And Under Can Now Freeze Their Eggs At Genetics & IVF Institute For Use In The Future
Genetics & IVF Institute (GIVF) is launching a Personal Egg Banking service in the Washington, DC area to help women 40 and under who want to cryopreserve (freeze) their eggs now for use in the future when they wish to become pregnant. The age of a woman's eggs dramatically affects her ability to conceive...

Below, you'll find extensive information on leading morning sickness pregnancy articles and products to help you on your way to success.

Heartburn During Pregnancy - When The Going Gets Tough
By Charles Johnson

Heartburn during pregnancy is a very common pregnancy problem. However, most women only suffer from heartburn on and off, during pregnancy. For some, it becomes more frequent; and rather difficult to handle. The most common cause that results in heartburn is that the baby is growing and so it puts extra pressure on the stomach. However, heartburn is not something that cannot be prevented. The following steps may help in it.

Prevention Of Heart Burn

You should remember the following:

*Intake of food should be done in small portions, rather than indulging in large meals.

*Alcohol and drinks containing caffeine, such as coffee, tea, and cola should be avoided.

*One should not lie down immediately after a meal.

*While sleeping, the bed should be in a tilted position, with the head raised high.

*Simple antacids like magnesium trisilicate can be taken, as they are not considered harmful.
Primarily, it has to be realized that heartburn during pregnancy cannot be avoided. Most women face it. However, what can be done is reduce the suffering through some simple measures.

What Is Heartburn And Why Does It Get Aggravated?

Let us now understand what exactly heartburn is and why does it get aggravated during pregnancy? When the acid from the stomach's digestive juices splashes up into the esophagus (gullet), it results in a burning sensation felt behind the breastbone - this in a layman's language is what is called as heartburn.

Anti-Hypertensive Drugs To Enhance Esophageal Contraction
Nifedipine, a calcium-channel blocker, was shown to decrease lower esophageal sphincter pressure and increase esophageal acid exposure time, while atenolol, a b1 blocker, was shown to inhibit relaxation of the smooth muscle of the esophagus...
New Endoscopic Treatment May Spare Barrett's Esophagus Patients From Surgery
Early tumor formation in Barrett's esophagus (BE) can be effectively and safely treated with radiofrequency ablation (RFA), in combination with prior endoscopic removal of visible lesions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute...
Shape Of Barrett's Epithelium Effects Prevalence Of Erosive Esophagitis
Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus. A research team from Yokohama City University School of Medicine hypothesized that some macroscopic features of Barrett's epithelium might be useful for identifying a subgroup with a high risk for the development of esophageal adenocarcinoma...
New Hope For Therapy In Heartburn-Related Cancer
Cancer of the gullet, or oesophagus, is one of the ten most common cancers in the Western world, and there have been recent alarming increases in the number of cases each year in the US and UK. There is no good treatment, and sufferers frequently face a short, painful battle which ends all too quickly in death. Many of the cancers diagnosed are in people with a long history of heartburn...
Development Of ADX10059 Ended For Long-Term Use
Addex Pharmaceuticals (SWISS: ADXN) announced that based on preliminary review of the unblinded data from study 206, it has terminated development of ADX10059 for chronic indications, including long term treatment of gastroesophageal reflux disease and migraine prophylaxis...
Amneal Receives FDA Approval For Nizatidine Oral Solution, The First Generic Oral Solution For Axid(R) In The Market
Amneal Pharmaceuticals is pleased to announce that it has received U.S. FDA approval to manufacture Nizatidine Oral Solution in the 15 mg/mL strength effective November 18, 2009. It is an AA-rated, therapeutically equivalent alternative to Axid® Oral Solution (a licensed trademark of Braintree Labs)...
Are Manometric Findings Different Between Patients With Erosive And Nonerosive Disease?
Gastroesophageal reflux disease (GERD) is defined as the pathological retrograde movement of gastric contents into the esophagus. Various esophageal motility disturbances which may be important in reflux are observed in patients with GERD. The main esophageal motility disorder in these patients is ineffective esophageal motility (IEM)...
Why Does Percutaneous Endoscopic Gastrostomy Fail To Eliminate Gastroesophageal Reflux?
Gastroesophageal reflux (GER) is a common problem in mechanically ventilated patients and contributes to the development of esophageal mucosal injury and even erosive esophagitis. The relationship between percutaneous endoscopic gastrostomy (PEG) and subsequent development of GER is complex and not well understood...
Strengthening Sphincters In Animals Via Muscle Cell Infusion
A new study shows that muscle cells grown in the lab can restore an intestine's ability to squeeze shut properly. The work, performed in dogs and rats, might ultimately help treat patients with conditions such as gastric reflux and fecal incontinence. This technique may be used to strengthen sphincters, which are the bands of muscle that separate the major sections of your intestinal tract...
FDA Approves ZEGERID OTC(TM) For Over-the-Counter Treatment Of Frequent Heartburn
Merck & Co., Inc. announced that the U.S. Food and Drug Administration (FDA) has approved ZEGERID OTC(TM) (omeprazole 20 mg/sodium bicarbonate 1100 mg capsules), for over-the-counter treatment of frequent heartburn. ZEGERID OTC will be marketed over-the-counter by Schering-Plough HealthCare Products, Inc., the consumer healthcare division of Merck & Co., Inc...
News From The November Issue Of GIE: Gastrointestinal Endoscopy
"Screening for Barrett's esophagus in asymptomatic women" Barrett's esophagus is a condition where the lining of the esophagus changes due to chronic inflammation, generally from gastroesophageal reflux disease (GERD). Barrett's esophagus is important to recognize as it may increase the risk of developing esophageal cancer...
Reflux Esophagitis Due To Immune Reaction, Not Acute Acid Burn
Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study. Rather, gastroesophageal reflux spurs the esophageal cells to release chemicals called cytokines, which attract inflammatory cells to the esophagus...
Addex ADX10059 Monotherapy Is Effective On GERD Symptoms In Phase IIb Clinical Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced that it achieved statistically significant efficacy on the primary endpoint, increasing the number of symptom free days in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mylan Receives FDA Approval For Generic Version Of Prevacid® Through Its Subsidiary Matrix Laboratories
Mylan Inc. (NASDAQ: MYL) announced that its privately held Indian subsidiary, Matrix Laboratories Limited, has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Lansoprazole Delayed-release (DR) Capsules, 15 mg and 30 mg. This product is shipping immediately and will be sold under the Mylan Pharmaceuticals brand...
Open Wide: Incisionless Surgery To Treat GERD
Every day, more than 20 percent of the U.S. population experiences the painful burning symptoms of gastroesophageal reflux disease (GERD). For these 20 million Americans, the first line of defense is medication...
FDA Approves New Salix Product Exclusively In Catalent's Zydis(R) Fast Dissolve Technology
Catalent Pharma Solutions, one of the leading advanced drug delivery technology providers to the pharmaceutical industry, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Metozolv™ ODT (orally disintegrating tablets) metoclopramide HCL utilizing Catalent's Zydis® fast dissolve technology...
Unexpected Consequences Of Proton Pump Inhibitor Use In Reflux Disease
Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these effects and prescribe these medications carefully, according to a new commentary published in the November 2009 issue of Otolaryngology -Head and Neck Surgery...
New Procedure For Acid Reflux/GERD
Boston Medical Center (BMC) surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD. Using the new procedure known as EsophyX TIF (Transoral Incisionless Fundaplication), surgeons can repair or reconstruct the valve between the esophagus and stomach, effectively stopping GERD...
New Studies Explore Connection Between High Stress And High Exposure Jobs And GI Disorders
In two new studies, presented at the American College of Gastroenterology's (ACG) 74th Annual Scientific meeting in San Diego, researchers explored the connection between high stress, high exposure occupations and long-term gastrointestinal disorders...
New Study Results Analyzed The Use Of KAPIDEX(TM) (dexlansoprazole) For Nighttime Heartburn In Adults With Non-Erosive GERD
New data being presented at the American College of Gastroenterology (ACG) 2009 Annual Scientific Meeting in San Diego showed that treatment with KAPIDEX(TM) (dexlansoprazole) delayed release capsules over a four-week period resulted in a statistically significant greater percentage of nights without heartburn in subjects with non-erosive gastroesophageal reflux disease (GERD),...
Possible Weight-Gain From Long-Term Treatment With Proton Pump Inhibitor
Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all grades of GERD, making these agents the mainstay of treatment...
XenoPort Announces Initiation Of A Phase 2b Clinical Trial Of Arbaclofen Placarbil In Patients With Gastroesophageal Reflux Disease
XenoPort, Inc. (Nasdaq:XNPT) announced today that it has initiated a Phase 2b clinical trial of arbaclofen placarbil (AP), also known as XP19986, in patients with gastroesophageal reflux disease (GERD) who remain symptomatic despite treatment with a proton pump inhibitor (PPI)...
Heartburn Drugs Deemed Safe For Fetuses According To Ben-Gurion University Researchers
H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev...
Addex Completes Enrollment Of First Mid-Stage Clinical GERD Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced the completion of enrollment in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mayo Clinic Researchers Lead National Clinical Trial Testing New Treatment For Chronic, Severe Indigestion
Could medicines used for depression also treat chronic, severe indigestion? Scientists at Mayo Clinic suspect they can and, backed by funding from the National Institutes of Health (NIH), they are testing that premise in a nationwide clinical trial...

It occurs mostly during the third trimester of pregnancy, when the baby has grown big enough to start putting pressure on the stomach.

Heartburn during pregnancy can be combated by maintaining a strict dietary regime. Foods that lead to heartburn should be avoided. This means, no fried or oily foods. High-fat food and processed food can lead to this problem. Soda and spicy food should also be avoided. A good and easy method of minimizing heartburn during pregnancy is to carry some chewing gum at all times. The gum helps in salivating, which helps to reduce the amount of the production of acid caused by heartburn.

During pregnancy, a woman's body undergoes many hormonal and physical changes - this also may result in heartburn. During pregnancy, a hormone called progesterone is produced that relaxes the muscles in the uterus. It also relaxes the muscles that control the way the food and liquid enter the stomach. With this particular muscle not functioning properly, heartburn becomes almost inevitable.

However, don't let all this information about heartburn during pregnancy scare you! There are many ways to fight heartburn. A lot of information is available on it. In addition, it is all just a click away. You could read more on pregnancy websites or visit a nearby store and pick up some pregnancy books for leisure reading. Heartburn sure has its disadvantages, but it cannot rob pregnancy of its many joys. All it requires is some care, and you can avoid it to a great extent.

We strive to provide only quality articles, so if there is a specific topic related to pregnancy heartburn that you would like us to cover, please contact us at any time.

And again, thank you to those contributing daily to our morning sickness pregnancy website.

Anti-Hypertensive Drugs To Enhance Esophageal Contraction
Nifedipine, a calcium-channel blocker, was shown to decrease lower esophageal sphincter pressure and increase esophageal acid exposure time, while atenolol, a b1 blocker, was shown to inhibit relaxation of the smooth muscle of the esophagus...
New Endoscopic Treatment May Spare Barrett's Esophagus Patients From Surgery
Early tumor formation in Barrett's esophagus (BE) can be effectively and safely treated with radiofrequency ablation (RFA), in combination with prior endoscopic removal of visible lesions, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute...
Shape Of Barrett's Epithelium Effects Prevalence Of Erosive Esophagitis
Barrett's epithelium is recognized as a complication of erosive esophagitis and is the pre-malignant condition for adenocarcinoma of the esophagus. A research team from Yokohama City University School of Medicine hypothesized that some macroscopic features of Barrett's epithelium might be useful for identifying a subgroup with a high risk for the development of esophageal adenocarcinoma...
New Hope For Therapy In Heartburn-Related Cancer
Cancer of the gullet, or oesophagus, is one of the ten most common cancers in the Western world, and there have been recent alarming increases in the number of cases each year in the US and UK. There is no good treatment, and sufferers frequently face a short, painful battle which ends all too quickly in death. Many of the cancers diagnosed are in people with a long history of heartburn...
Development Of ADX10059 Ended For Long-Term Use
Addex Pharmaceuticals (SWISS: ADXN) announced that based on preliminary review of the unblinded data from study 206, it has terminated development of ADX10059 for chronic indications, including long term treatment of gastroesophageal reflux disease and migraine prophylaxis...
Amneal Receives FDA Approval For Nizatidine Oral Solution, The First Generic Oral Solution For Axid(R) In The Market
Amneal Pharmaceuticals is pleased to announce that it has received U.S. FDA approval to manufacture Nizatidine Oral Solution in the 15 mg/mL strength effective November 18, 2009. It is an AA-rated, therapeutically equivalent alternative to Axid® Oral Solution (a licensed trademark of Braintree Labs)...
Are Manometric Findings Different Between Patients With Erosive And Nonerosive Disease?
Gastroesophageal reflux disease (GERD) is defined as the pathological retrograde movement of gastric contents into the esophagus. Various esophageal motility disturbances which may be important in reflux are observed in patients with GERD. The main esophageal motility disorder in these patients is ineffective esophageal motility (IEM)...
Why Does Percutaneous Endoscopic Gastrostomy Fail To Eliminate Gastroesophageal Reflux?
Gastroesophageal reflux (GER) is a common problem in mechanically ventilated patients and contributes to the development of esophageal mucosal injury and even erosive esophagitis. The relationship between percutaneous endoscopic gastrostomy (PEG) and subsequent development of GER is complex and not well understood...
Strengthening Sphincters In Animals Via Muscle Cell Infusion
A new study shows that muscle cells grown in the lab can restore an intestine's ability to squeeze shut properly. The work, performed in dogs and rats, might ultimately help treat patients with conditions such as gastric reflux and fecal incontinence. This technique may be used to strengthen sphincters, which are the bands of muscle that separate the major sections of your intestinal tract...
FDA Approves ZEGERID OTC(TM) For Over-the-Counter Treatment Of Frequent Heartburn
Merck & Co., Inc. announced that the U.S. Food and Drug Administration (FDA) has approved ZEGERID OTC(TM) (omeprazole 20 mg/sodium bicarbonate 1100 mg capsules), for over-the-counter treatment of frequent heartburn. ZEGERID OTC will be marketed over-the-counter by Schering-Plough HealthCare Products, Inc., the consumer healthcare division of Merck & Co., Inc...
News From The November Issue Of GIE: Gastrointestinal Endoscopy
"Screening for Barrett's esophagus in asymptomatic women" Barrett's esophagus is a condition where the lining of the esophagus changes due to chronic inflammation, generally from gastroesophageal reflux disease (GERD). Barrett's esophagus is important to recognize as it may increase the risk of developing esophageal cancer...
Reflux Esophagitis Due To Immune Reaction, Not Acute Acid Burn
Contrary to current thinking, a condition called gastroesophageal reflux disease (GERD) might not develop as a direct result of acidic digestive juices burning the esophagus, UT Southwestern Medical Center researchers have found in an animal study. Rather, gastroesophageal reflux spurs the esophageal cells to release chemicals called cytokines, which attract inflammatory cells to the esophagus...
Addex ADX10059 Monotherapy Is Effective On GERD Symptoms In Phase IIb Clinical Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced that it achieved statistically significant efficacy on the primary endpoint, increasing the number of symptom free days in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mylan Receives FDA Approval For Generic Version Of Prevacid® Through Its Subsidiary Matrix Laboratories
Mylan Inc. (NASDAQ: MYL) announced that its privately held Indian subsidiary, Matrix Laboratories Limited, has received final approval from the U.S. Food and Drug Administration (FDA) for its Abbreviated New Drug Application (ANDA) for Lansoprazole Delayed-release (DR) Capsules, 15 mg and 30 mg. This product is shipping immediately and will be sold under the Mylan Pharmaceuticals brand...
Open Wide: Incisionless Surgery To Treat GERD
Every day, more than 20 percent of the U.S. population experiences the painful burning symptoms of gastroesophageal reflux disease (GERD). For these 20 million Americans, the first line of defense is medication...
FDA Approves New Salix Product Exclusively In Catalent's Zydis(R) Fast Dissolve Technology
Catalent Pharma Solutions, one of the leading advanced drug delivery technology providers to the pharmaceutical industry, announced that the U.S. Food and Drug Administration (FDA) has granted marketing approval for Metozolv™ ODT (orally disintegrating tablets) metoclopramide HCL utilizing Catalent's Zydis® fast dissolve technology...
Unexpected Consequences Of Proton Pump Inhibitor Use In Reflux Disease
Despite being highly effective and beneficial for many patients, unexpected consequences are emerging in patients who are prescribed proton pump inhibitors (PPIs) for reflux diseases. Physicians are warned to monitor these effects and prescribe these medications carefully, according to a new commentary published in the November 2009 issue of Otolaryngology -Head and Neck Surgery...
New Procedure For Acid Reflux/GERD
Boston Medical Center (BMC) surgeons are now offering patients an incisionless alternative to laparoscopic and traditional surgery for treatment of acid reflux or GERD. Using the new procedure known as EsophyX TIF (Transoral Incisionless Fundaplication), surgeons can repair or reconstruct the valve between the esophagus and stomach, effectively stopping GERD...
New Studies Explore Connection Between High Stress And High Exposure Jobs And GI Disorders
In two new studies, presented at the American College of Gastroenterology's (ACG) 74th Annual Scientific meeting in San Diego, researchers explored the connection between high stress, high exposure occupations and long-term gastrointestinal disorders...
New Study Results Analyzed The Use Of KAPIDEX(TM) (dexlansoprazole) For Nighttime Heartburn In Adults With Non-Erosive GERD
New data being presented at the American College of Gastroenterology (ACG) 2009 Annual Scientific Meeting in San Diego showed that treatment with KAPIDEX(TM) (dexlansoprazole) delayed release capsules over a four-week period resulted in a statistically significant greater percentage of nights without heartburn in subjects with non-erosive gastroesophageal reflux disease (GERD),...
Possible Weight-Gain From Long-Term Treatment With Proton Pump Inhibitor
Gastroesophageal reflux disease (GERD) is the most common esophageal disorder, and frequently encountered in the primary care setting. Accumulating evidence has confirmed the excellent efficacy and safety of proton pump inhibitor (PPI) therapy in patients with all grades of GERD, making these agents the mainstay of treatment...
XenoPort Announces Initiation Of A Phase 2b Clinical Trial Of Arbaclofen Placarbil In Patients With Gastroesophageal Reflux Disease
XenoPort, Inc. (Nasdaq:XNPT) announced today that it has initiated a Phase 2b clinical trial of arbaclofen placarbil (AP), also known as XP19986, in patients with gastroesophageal reflux disease (GERD) who remain symptomatic despite treatment with a proton pump inhibitor (PPI)...
Heartburn Drugs Deemed Safe For Fetuses According To Ben-Gurion University Researchers
H2 Blocker drugs, such as Famotidine, Cimetidine and Ranitidine, approved in the U.S. for acid reflux (heartburn), pose no significant risks for the fetus according to a large collaborative cohort study by researchers at Ben-Gurion University of the Negev...
Addex Completes Enrollment Of First Mid-Stage Clinical GERD Trial
Addex Pharmaceuticals (SWISS: ADXN), the allosteric modulation company, announced the completion of enrollment in the Phase IIb trial of ADX10059 as a monotherapy in patients with gastroesophageal reflux disease (GERD), the cause of heartburn and other symptoms...
Mayo Clinic Researchers Lead National Clinical Trial Testing New Treatment For Chronic, Severe Indigestion
Could medicines used for depression also treat chronic, severe indigestion? Scientists at Mayo Clinic suspect they can and, backed by funding from the National Institutes of Health (NIH), they are testing that premise in a nationwide clinical trial...